Article
The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
Radiation oncology (London, England) - 25 Sept 2008
Chinnaiyan Prakash, Wang Meihua, Rojiani Amyn M, Tofilon Philip J, Chakravarti Arnab, Ang K Kian, Zhang Hua-Zhong, Hammond Elizabeth, Curran Walter, Mehta Minesh P
Abstract excerpt
BACKGROUND: Nestin is an intermediate filament protein that has been implicated in early stages of neuronal lineage commitment. Based on the heterogeneous expression of nestin in GBM and its potential to serve as a marker for a dedifferentiated, and perhaps more aggressive phenotype, the Radiation Therapy Oncology Group (RTOG) sought to determine the prognostic value of nestin expression in newly diagnosed GBM...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.