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Article

Follicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells.

International journal of cancer - 1 Jan 2009

Ai Weiyun Z, Hou Jing-Zhou, Zeiser Robert, Czerwinski Debra, Negrin Robert S, Levy Ronald

Abstract excerpt

There has been accumulating evidence that CD4(+)CD25(+) FoxP3 expressing regulatory T cells (Treg) are highly concentrated in tumors, thereby fostering an immune-privileged microenvironment. Some studies have shown that T-cell receptor (TCR) stimulation can convert conventional T cells into Treg. Follicular lymphoma (FL) B cells can enhance this Treg conversion. We investigated whether FL tumor B cells, as...

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Identifiers

PMID: 18814264
DOI: 10.1002/ijc.23881
PMCID: PMC2631275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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