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Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum‐free medium

22 Sept 2008

Abstract excerpt

Formation of the primitive streak (PS) is the initial specification step that generates all the mesodermal and endodermal tissue lineages during early differentiation. Thus, a therapeutically compatible and efficient method for differentiation of the PS is crucial for regenerative medicine. In this study, we developed chemically defined serum‐free culture conditions for the differentiation of embryonic stem (ES)...

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PMID: 18809738
DOI: 10.1096/fj.08-111203

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