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Article

Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer

23 Sept 2008

Abstract excerpt

PURPOSE: Identifying individuals with Lynch syndrome (LS) is highly beneficial. However, it is unclear whether microsatellite instability (MSI) or immunohistochemistry (IHC) should be used as the screening test and whether screening should target all patients with colorectal cancer (CRC) or those in high-risk subgroups. PATIENTS AND METHODS: MSI testing and IHC for the four mismatch repair proteins was performed...

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Identifiers

PMID: 18809606
DOI: 10.1200/jco.2008.17.5950

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