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Article

Population-based molecular screening for Lynch syndrome: implications for personalized medicine.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jul 2013

Ward Robyn L, Hicks Sian, Hawkins Nicholas J

Abstract excerpt

PURPOSE: Molecular screening techniques are available to identify hereditary Lynch syndrome in people with newly diagnosed colorectal cancer (CRC). We aimed to determine whether decisions of patients or clinicians reduced detection of Lynch syndrome. PATIENTS AND METHODS: A prospective cohort of 245 consecutive individuals with mismatch repair-deficient CRC recruited from a population-based molecular screening...

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Identifiers

PMID: 23733757
DOI: 10.1200/JCO.2012.46.8454

Genes

BRAF

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Related research

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Research trail→

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Lynch Syndrome: From Screening to Diagnosis to Treatment in the Era of Modern Molecular OncologySemantic proximity Read ↗

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Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention InitiativeSemantic proximity Read ↗

Cancer risk in Lynch Syndrome.Semantic proximity Read ↗

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