Flow cytometric analysis of the phenotypic distribution of splenic lymphocytes in zinc-deficient adult mice.

Abstract excerpt

Many immunodeficiency states create an imbalance in the ratio of T cells to B cells or in the subsets of lymphocytes found within these two major classes. A 30-d period of suboptimal intake of zinc often caused a 50% decrease in the total number of splenic lymphocytes in young adult mice. One- and two-color flow cytometric analysis was made of the residual splenocytes of the zinc-deficient mice to determine...

Topics

• Animals
• Antigens, Surface
• B-Lymphocyte Subsets
• Body Weight
• Diet
• Female
• Flow Cytometry
• Mice
• Phenotype
• Spleen
• T-Lymphocyte Subsets
• Zinc