Article
Flow cytometric analysis of the phenotypic distribution of splenic lymphocytes in zinc-deficient adult mice.
The Journal of nutrition - 1 Sept 1991
King L E, Fraker P J
Abstract excerpt
Many immunodeficiency states create an imbalance in the ratio of T cells to B cells or in the subsets of lymphocytes found within these two major classes. A 30-d period of suboptimal intake of zinc often caused a 50% decrease in the total number of splenic lymphocytes in young adult mice. One- and two-color flow cytometric analysis was made of the residual splenocytes of the zinc-deficient mice to determine...
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