Article
Folate receptor expression in pituitary adenomas cellular and molecular analysis.
Vitamins and hormones - 1 Jan 2008
Evans Chheng-Orn, Yao Congjun, Laborde David, Oyesiku Nelson M
Abstract excerpt
Clinically nonfunctional pituitary adenomas cause hypopituitarism or compression of regional structures. Unlike functional tumors, there is no available medical treatment or specific imaging technique for these tumors. We have recently discovered that both folate receptor (FR)alpha mRNA and protein are uniquely overexpressed in nonfunctional pituitary tumors, but not in functional adenomas. We hypothesized that...
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