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Article

Detailed analysis of the serotonin transporter gene (SLC6A4) shows no association with bipolar disorder in the Northern Swedish population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2009

Alaerts Maaike, Ceulemans Shana, Forero Diego, Moens Lotte N, De Zutter Sonia, Heyrman Lien, Lenaerts An-Sofie, Norrback Karl-Fredrik, Goossens Dirk, De Rijk Peter, Nilsson Lars-Göran, Adolfsson Rolf, Del-Favero Jurgen

Abstract excerpt

Through active reuptake of serotonin into presynaptic neurons, the serotonin transporter (5-HTT) plays an important role in regulating serotonin concentrations in the brain, and it is the site of binding for tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs). Therefore it has been hypothesized that this transporter is involved in the etiology of bipolar (BP) disorder. Inconsistent...

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Source

Identifiers

PMID: 18792946
DOI: 10.1002/ajmg.b.30853

Genes

BPI
HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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