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Article

Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes.

Osteoarthritis and cartilage - 1 Mar 2009

Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco F J, Meulenbelt I, Slagboom P E, Valdes A M, Spector T D, Gomez-Reino J J, Gonzalez A

Abstract excerpt

OBJECTIVE: To investigate the effect in OA (Osteoarthritis) susceptibility of putative damaging changes in ADAM (A Disintegrin And Metalloprotease) and ADAMTS (ADAM with ThromboSpondin motif) proteases. METHODS: Non-synonymous single nucleotide polymorphisms (nsSNP) in 18 ADAMTS and 31 ADAM genes were analyzed with two software applications for prediction of functional damage. Four putative damaging nsSNP were...

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Source

Identifiers

PMID: 18790654
DOI: 10.1016/j.joca.2008.07.012

Genes

ADAMTS14
ADAM12
ADAMTS16
ADAMTS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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