Article
Adjustment of genomic waves in signal intensities from whole-genome SNP genotyping platforms.
Nucleic acids research - 1 Nov 2008
Diskin Sharon J, Li Mingyao, Hou Cuiping, Yang Shuzhang, Glessner Joseph, Hakonarson Hakon, Bucan Maja, Maris John M, Wang Kai
Abstract excerpt
Whole-genome microarrays with large-insert clones designed to determine DNA copy number often show variation in hybridization intensity that is related to the genomic position of the clones. We found these 'genomic waves' to be present in Illumina and Affymetrix SNP genotyping arrays, confirming...
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