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Article

NHERF1 mutations and responsiveness of renal parathyroid hormone.

The New England journal of medicine - 11 Sept 2008

Karim Zoubida, Gérard Bénédicte, Bakouh Naziha, Alili Rohia, Leroy Christine, Beck Laurent, Silve Caroline, Planelles Gabrielle, Urena-Torres Pablo, Grandchamp Bernard, Friedlander Gérard, Prié Dominique

Abstract excerpt

Impaired renal phosphate reabsorption, as measured by dividing the tubular maximal reabsorption of phosphate by the glomerular filtration rate (TmP/GFR), increases the risks of nephrolithiasis and bone demineralization. Data from animal models suggest that sodium-hydrogen exchanger regulatory factor 1 (NHERF1) controls renal phosphate transport. We sequenced the NHERF1 gene in 158 patients, 94 of whom had either...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18784102
DOI: 10.1056/NEJMoa0802836

Genes

NHERF1
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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