Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-environment interaction between MBL2 genotype and smoking, and the risk of gram-positive bacteraemia.

Scandinavian journal of immunology - 1 Oct 2008

Huttunen R, Aittoniemi J, Laine J, Vuento R, Karjalainen J, Rovio A T, Eklund C, Hurme M, Huhtala H, Syrjänen J

Abstract excerpt

Mannose-binding lectin (MBL) insufficiency caused by point mutations in the MBL2 gene has been associated with increased susceptibility to bacteraemic infections. We here investigated the effect of MBL2 polymorphisms on the susceptibility and clinical course of bacteraemia. The study cohort comprised 145 patients with bacteraemia and 400 controls. In the case of patients with bacteraemia, laboratory findings and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacteremia

Share to Gram-Positive Bacterial Infections

Share to Mannose-Binding Lectin

Share to Promoter Regions, Genetic

Share to Risk Factors

Share to Smoking

Source

Identifiers

PMID: 18782274
DOI: 10.1111/j.1365-3083.2008.02149.x

Genes

MBL2
GAA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-environment interaction between MBL2 genotype and smoking, and the risk of gram-positive bacteraemia.PMID 18782274Read ↗

Smoking status interacts with the association between mannose-binding lectin serum levels and gene polymorphism and the carriage of oropharyngeal bacteria.Semantic proximity Read ↗

Genetic susceptibility to invasive meningococcal disease: MBL2 structural polymorphisms revisited in a large case-control study and a systematic review.Semantic proximity Read ↗

Genetic variants of the MBL2 gene are associated with mortality in pneumococcal sepsis.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections.Semantic proximity Read ↗

Mannose binding lectin gene 2 (rs1800450) missense variant may contribute to development and severity of COVID-19 infection.Semantic proximity Read ↗

Association between mannose-binding lectin deficiency and septic shock following acute pyelonephritis due to Escherichia coli.Semantic proximity Read ↗

Heterozygosity of mannose-binding lectin (MBL2) genotypes predicts advantage (heterosis) in relation to fatal outcome in intensive care patientsSemantic proximity Read ↗

Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort.Semantic proximity Read ↗

Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphism in relation to periodontal infection.Semantic proximity Read ↗

Mannose-binding lectin 2 (Mbl2) gene polymorphisms are related to protein plasma levels, but not to heart disease and infection by Chlamydia.Semantic proximity Read ↗

Study of the effect of DNA polymorphisms in the mannose-binding lectin gene (MBL2) on disease severity in Slovak cystic fibrosis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.