Article
Brain lipid composition in grey-lethal mutant mouse characterized by severe malignant osteopetrosis.
Glycoconjugate journal - 1 Aug 2009
Prinetti Alessandro, Rocchetta Federica, Costantino Elvira, Frattini Annalisa, Caldana Elena, Rucci Francesca, Bettiga Arianna, Poliani Pietro L, Chigorno Vanna, Sonnino Sandro
Abstract excerpt
The grey-lethal mouse (gl/gl) mutant most closely resembles the severe human malignant autosomal recessive OSTM1-dependent form of osteopetrosis that it has been described to be associated with neurological abnormalities. For this reason, we have analyzed the brain lipid composition (gangliosides, neutral glycosphingolipids, phospholipids and cholesterol), from gl/gl mice at different ages of development and...
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