Article
Physical activity and the association of common FTO gene variants with body mass index and obesity.
Archives of internal medicine - 8 Sept 2008
Rampersaud Evadnie, Mitchell Braxton D, Pollin Toni I, Fu Mao, Shen Haiqing, O'Connell Jeffery R, Ducharme Julie L, Hines Scott, Sack Paul, Naglieri Rosalie, Shuldiner Alan R, Snitker Soren
Abstract excerpt
BACKGROUND: Common FTO (fat mass and obesity associated) gene variants have recently been associated with body mass index (BMI) and obesity in several large studies. The role of lifestyle factors (such as physical activity) in those with an underlying FTO genetic predisposition is unknown. METHODS: To determine if FTO variants are associated with BMI in Old Order Amish (OOA) individuals, and to further determine...
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