Article
Maintenance time of sedative effects after an intravenous infusion of diazepam: a guide for endoscopy using diazepam.
World journal of gastroenterology - 7 Sept 2008
Sugimoto Mitsushige, Furuta Takahisa, Nakamura Akiko, Shirai Naohito, Ikuma Mutsuhiro, Misaka Shingen, Uchida Shinya, Watanabe Hiroshi, Ohashi Kyoichi, Ishizaki Takashi, Hishida Akira
Abstract excerpt
AIM: To examine whether the sedative effects assessed by psychomotor tests would depend on the cytochrome P450 (CYP) 2C19 genotypes after an infusion regimen of diazepam commonly used for gastrointestinal endoscopy in Japan. METHODS: Fifteen healthy Japanese volunteers consisting of three differe...
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