Article
Genetic association between aldehyde dehydrogenase 2 (ALDH2) variation and high-density lipoprotein cholesterol (HDL-C) among non-drinkers in two large population samples in Japan.
Journal of atherosclerosis and thrombosis - 1 Aug 2008
Wada Manabu, Daimon Makoto, Emi Mitsuru, Iijima Hiroshi, Sato Hidenori, Koyano Satoru, Tajima Katsushi, Kawanami Toru, Kurita Keiji, Hunt Steven C, Hopkins Paul N, Kubota Isao, Kawata Sumio, Kato Takeo
Abstract excerpt
AIM: Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL-C levels has not been proven. We undertook a large-scale correlation study between HDL-C...
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