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Article

Sperm Chromatin Structure Assay: Its Clinical Use for Detecting Sperm DNA Fragmentation in Male Infertility and Comparisons With Other Techniques

2 Jan 2002

Abstract excerpt

The Sperm Chromatin Structure Assay (SCSA) was first described in the December 5, 1980 issue of Science (Evenson et al, 1980a). The data described in that article showed a significant difference between proven fertile and subfertility or infertility in men and bulls and the susceptibility to denaturation of their sperm nuclear DNA. A subsequent study The data were heterogeneous, and begged the question, what was...

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PMID: 11780920
DOI: 10.1002/j.1939-4640.2002.tb02599.x

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