Article
Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2008
Canedo Paulo, Durães Cecília, Pereira Fábio, Regalo Gonçalo, Lunet Nuno, Barros Henrique, Carneiro Fátima, Seruca Raquel, Rocha Jorge, Machado José C
Abstract excerpt
The tumor necrosis factor alpha (TNFA)-308*A allele has been found to confer an increased risk of gastric carcinoma. Inconsistency in risk estimates across populations lead us to hypothesize about the presence of an alternative causal locus in the same chromosomal region. A suitable approach is to determine the tumor necrosis factor haplotypic structure in order to clarify whether the association between the *A...
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