Article
Alleles of the estrogen receptor alpha-gene and an estrogen receptor cotranscriptional activator gene, amplified in breast cancer-1 (AIB1), are associated with quantitative calcaneal ultrasound.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2000
Patel M S, Cole D E, Smith J D, Hawker G A, Wong B, Trang H, Vieth R, Meltzer P, Rubin L A
Abstract excerpt
Quantitative bone ultrasound (QUS) has a significant heritable component. Because estrogen is required for attainment of peak bone mass, we studied alleles of two genes, estrogen receptor alpha (ER1) and amplified in breast cancer-1 (AIB1), for their association with QUS. In a volunteer sample of 663 white women aged 18-35 years, bone ultrasound attenuation (BUA), speed of sound (SOS), and heel stiffness index...
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