Article
Genetic stability of the live attenuated Bordetella pertussis vaccine candidate BPZE1.
Vaccine - 23 Oct 2008
Feunou Pascal Feunou, Ismaili Jamila, Debrie Anne-Sophie, Huot Ludovic, Hot David, Raze Dominique, Lemoine Yves, Locht Camille
Abstract excerpt
Despite the extensive use of efficacious pertussis vaccines, Bordetella pertussis infections are still among the main causes for childhood morbidity and mortality. Severe pertussis occurs mostly in very young children, often too young to be sufficiently protected by current vaccines, which require several administrations in regimens that vary between countries. Since natural infection with B. pertussis is able to...
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