Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jan 2009

Otaegui D, Zuriarrain O, Castillo-Triviño T, Aransay Am, Ruíz-Martinez J, Olaskoaga J, Marti-Masso Jf, Lopez de Munain A

Abstract excerpt

BACKGROUND: Synapsins are a family of neuron-specific phosphoproteins, one of whose subunits is encoded by the SYN3 gene. This gene is located close to one of the multiple sclerosis susceptibility regions (in 22q13.1). Two single-nucleotide polymorphisms (SNPs) (rs133945 and rs133946) in the promoter region of this gene have been proposed as factors protecting against MS. This relationship is not clear because...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethnicity
Share to Multiple Sclerosis, Chronic Progressive
Share to Multiple Sclerosis, Relapsing-Remitting
Share to Polymerase Chain Reaction
Share to Polymorphism, Single Nucleotide
Share to Promoter Regions, Genetic
Share to Spain
Share to Synapsins

Source

Identifiers

PMID: 18755822
DOI: 10.1177/1352458508096682

Genes

SYN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients.PMID 18755822Read ↗

Association between Synapsin III gene promoter polymorphisms and multiple sclerosis.Semantic proximity Read ↗

Positive association between synapsin II and schizophrenia.Semantic proximity Read ↗

Synapsin III gene polymorphisms and schizophrenia.Semantic proximity Read ↗

Mutational analysis of the synapsin III gene on chromosome 22q12-q13 in schizophrenia.Semantic proximity Read ↗

Association and expression study of synapsin III and schizophrenia.Semantic proximity Read ↗

Mutation analysis of synapsin III gene in schizophrenia.Semantic proximity Read ↗

Single nucleotide polymorphisms in the FOXP3 gene are associated with increased risk of relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia.Semantic proximity Read ↗

The 795CT polymorphism in osteopontin gene is not associated with multiple sclerosis in a Spanish population.Semantic proximity Read ↗

Identification of single nucleotide variations in the coding and regulatory regions of the myelin-associated glycoprotein gene and study of their association with multiple sclerosis.Semantic proximity Read ↗

Association of synapsin III gene with adult attention deficit hyperactivity disorder.Semantic proximity Read ↗

The osteopontin gene +1239A/C single nucleotide polymorphism is associated with type 1 diabetes mellitus in the Italian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.