Article
Mutation analysis of synapsin III gene in schizophrenia.
American journal of medical genetics - 8 Jan 2002
Tsai Ming-Ta, Hung Chao-Chun, Tsai Chan-Yen, Liu Mei-Ying, Su Yi-Chieh, Chen Yun-Hsiang, Hsiao Kwang-Jen, Chen Chia-Hsiang
Abstract excerpt
Synapsin III is a new synapsin family gene with the putative function of synaptogenesis regulation and neurotransmitter release in the brain. The gene was mapped to 22q12-q13, a schizophrenia susceptible region gene as suggested by several linkage studies. Hence, the synapsin III gene is considered a candidate gene of schizophrenia. We systematically sequenced the protein coding and 5'-promoter regions of the...
Topics
- Asian People
- DNA Mutational Analysis
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Neuropeptides
- Phosphoproteins
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Schizophrenia
- Synapsins
- Taiwan