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Article

Ganglioside GM1 Mediates Decapacitation Effects of SVS2 on Murine Spermatozoa1

28 Aug 2008

Abstract excerpt

Prior to fertilization, mammalian spermatozoa need to acquire fertilizing ability (capacitation) in the female reproductive tract. On the other hand, capacitated spermatozoa reversibly lose their capacitated state when treated with seminal plasma (decapacitation). Previously, we demonstrated that a mouse seminal plasma protein, SVS2, is a decapacitation factor and regulates sperm fertilizing ability in vivo....

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Share to Lipid metabolism and biosynthesis
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PMID: 18753612
DOI: 10.1095/biolreprod.108.069054

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