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Article

Reorganization of Lipid Rafts During Capacitation of Human Sperm1

1 Oct 2004

Abstract excerpt

Ejaculated mammalian sperm must complete a final maturation, termed capacitation, before they can undergo acrosomal exocytosis and fertilize an egg. In human sperm, loss of sperm sterol is an obligatory, early event in capacitation. How sterol loss leads to acrosomal responsiveness is unknown. These experiments tested the hypothesis that loss of sperm sterol affects the organization of cold detergent-resistant...

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PMID: 15215196
DOI: 10.1095/biolreprod.104.030502

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