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Article

A mouse sperm decapacitation factor receptor is phosphatidylethanolamine-binding protein 1

23 Sept 2005

Abstract excerpt

Capacitation is a pivotal event for mammalian spermatozoa, involving the loss of surface proteins known as decapacitation factors (DF) and consequent acquisition of fertilizing ability. Earlier studies showed that a mouse sperm DF binds to a receptor, DF-R, whose attachment to the sperm plasma membrane appears to involve a glycosylphosphatidylinositol (GPI) anchor. In the present study, purification and...

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PMID: 16183867
DOI: 10.1530/rep.1.00792

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