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Article

Evidence for the Involvement of Testicular Protein CRISP2 in Mouse Sperm-Egg Fusion1

4 Jan 2007

Abstract excerpt

CRISP2, originally known as Tpx-1, is a cysteine-rich secretory protein specifically expressed in male haploid germ cells. Although likely to be involved in gamete interaction, evidence for a functional role of CRISP2 in fertilization still remains poor. In the present study, we used a mouse model to examine the subcellular localization of CRISP2 in sperm and its involvement in the different stages of...

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PMID: 17202389
DOI: 10.1095/biolreprod.106.056770

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Related research

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Research trail→

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Evidence for the Involvement of Testicular Protein CRISP2 in Mouse Sperm-Egg Fusion1PMID 17202389Read ↗

A Novel Function for CRISP1 in Rodent Fertilization: Involvement in Sperm-Zona Pellucida Interaction1Semantic proximity Read ↗

Participation of cysteine-rich secretory proteins (CRISP) in mammalian sperm-egg interactionSemantic proximity Read ↗

From the epididymis to the egg: participation of CRISP proteins in mammalian fertilizationSemantic proximity Read ↗

Epididymal Protein CRISP1 Plays Different Roles During the Fertilization ProcessSemantic proximity Read ↗

Cysteine-Rich Secretory Proteins (CRISP) are Key Players in Mammalian Fertilization and FertilitySemantic proximity Read ↗

CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male FertilitySemantic proximity Read ↗

Fertilization defects in sperm from<i>Cysteine-rich secretory protein 2</i>(<i>Crisp2</i>) knockout mice: implications for fertility disordersSemantic proximity Read ↗

Relevance of CRISP proteins for epididymal physiology, fertilization, and fertilitySemantic proximity Read ↗

Mouse Cysteine-Rich Secretory Protein 4 (CRISP4): A Member of the Crisp Family Exclusively Expressed in the Epididymis in an Androgen-Dependent Manner1Semantic proximity Read ↗

Loss of Cysteine-Rich Secretory Protein 4 (Crisp4) Leads to Deficiency in Sperm-Zona Pellucida Interaction in Mice1Semantic proximity Read ↗

Participation of epididymal cysteine-rich secretory proteins in sperm-egg fusion and their potential use for male fertility regulationSemantic proximity Read ↗

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4Semantic proximity Read ↗

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