Article
Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses.
Retrovirology - 20 Mar 2012
Kraft Colleen S, Basu Debby, Hawkins Paulina A, Hraber Peter T, Chomba Elwyn, Mulenga Joseph, Kilembe William, Khu Naw H, Derdeyn Cynthia A, Allen Susan A, Manigart Olivier, Hunter Eric
Abstract excerpt
BACKGROUND: HIV-1 superinfection occurs at varying frequencies in different at risk populations. Though seroincidence is decreased, in the negative partner of HIV-discordant couples after joint testing and counseling in the Zambia Emory HIV Research Project (ZEHRP) cohort, the annual infection rate remains relatively high at 7-8%. Based on sequencing within the gp41 region of each partner's virus, 24% of new...
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