Article
A clinical guide to autoinflammatory diseases: familial Mediterranean fever and next-of-kin.
Nature reviews. Rheumatology - 1 Mar 2014
Ozen Seza, Bilginer Yelda
Abstract excerpt
Autoinflammatory diseases are associated with abnormal activation of the innate immune system, leading to clinical inflammation and high levels of acute-phase reactants. The first group to be identified was the periodic fever diseases, of which familial Mediterranean fever (FMF) is the most common. In FMF, genetic results are not always straightforward; thus, flowcharts to guide the physician in requesting...
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