Article
SNAP-25 genotype influences NAA/Cho in left hippocampus.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2008
Scherk Harald, Backens Martin, Zill Peter, Schneider-Axmann Thomas, Wobrock Thomas, Usher Juliana, Reith Wolfgang, Falkai Peter, Möller Hans-Jürgen, Bondy Brigitta, Gruber Oliver
Abstract excerpt
The SNAP-25 gene is an integral part of the vesicle docking and fusion machinery that controls neurotransmitter release. Several post mortem studies revealed a reduction of SNAP-25 protein in the hippocampus of patients with schizophrenia and bipolar disorder (BD). Thirty-eight patients with schizophrenia, BD or obsessive-compulsive disorder and 17 healthy controls participated in the study. Proton magnetic...
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