Article
No association between epidermal growth factor and epidermal growth factor receptor polymorphisms and nasopharyngeal carcinoma.
Cancer genetics and cytogenetics - 1 Sept 2008
Gao Lin-Bo, Wei Ye-Sheng, Zhou Bin, Wang Yan-Yun, Liang Wei-Bo, Li Cui, Li Yi, Bai Peng, Fang Wen-Liang, Xue Hui, Zhang Lin
Abstract excerpt
Numerous candidate genes have been proposed as susceptibility factors for the development of nasopharyngeal carcinoma (NPC). Epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) interaction plays a pivotal role in cell proliferation, differentiation, and tumourigenesis of epithelial tissues. To our knowledge, however, no study has examined the relationship between the EGF/EGFR and NPC. The...
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