Article
A parylene-based dual channel micro-electrophoresis system for rapid mutation detection via heteroduplex analysis.
Electrophoresis - 1 Sept 2008
Sukas Sertan, Erson Ayse Elif, Sert Cuneyt, Kulah Haluk
Abstract excerpt
A new dual channel micro-electrophoresis system for rapid mutation detection based on heteroduplex analysis was designed and implemented. Mutation detection was successfully achieved in a total separation length of 250 microm in less than 3 min for a 590 bp DNA sample harboring a 3 bp mutation causing an amino acid change. Parylene-C was used as the structural material for fabricating the micro-channels as it...
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