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Article

Analysis of the association of preeclampsia with polymorphisms of the INS, INSR and IRS1 genes in Mexican women.

Gynecologic and obstetric investigation - 1 Jan 2009

Machorro-Lazo Maria-Victoria, Sanchez-Corona Jose, Martínez-Abundis Esperanza, González-Ortiz Manuel, Galaviz-Hernandez Carlos, Perea Francisco-Javier, Garcia-Zapien Alejandra-Guadalupe, Cruz-Quevedo Edhit-Guadalupe, Salgado-Goytia Lorenzo, Moran-Moguel Maria-Cristina, Flores-Martínez Silvia-Esperanza

Abstract excerpt

BACKGROUND/AIMS: It has been proposed that preeclampsia is a metabolic syndrome of pregnancy. The polymorphisms PstI and MaeIII of INS, NsiI of INSR and Ala513Pro and Gly972Arg of IRS1 have been associated with metabolic syndrome; moreover, the products of these genes are functionally contiguous during insulin signaling. The aim of this study was to assess whether these polymorphisms are associated with...

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Source

Identifiers

PMID: 18716398
DOI: 10.1159/000151500

Genes

INS
INSR
IRS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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