Article
Motor neuron regeneration in adult zebrafish.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Aug 2008
Reimer Michell M, Sörensen Inga, Kuscha Veronika, Frank Rebecca E, Liu Chong, Becker Catherina G, Becker Thomas
Abstract excerpt
The mammalian spinal cord does not regenerate motor neurons that are lost as a result of injury or disease. Here we demonstrate that adult zebrafish, which show functional spinal cord regeneration, are capable of motor neuron regeneration. After a spinal lesion, the ventricular zone shows a widespread increase in proliferation, including slowly proliferating olig2-positive (olig2+) ependymo-radial glial...
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