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Article

Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity.

PloS one - 20 Aug 2008

Coleman Adam S, Yang Xiuli, Kumar Manish, Zhang Xinyue, Promnares Kamoltip, Shroder Deborah, Kenedy Melisha R, Anderson John F, Akins Darrin R, Pal Utpal

Abstract excerpt

Borrelia burgdorferi, the pathogen of Lyme disease, cycles in nature through Ixodes ticks and mammalian hosts. At least five Complement Regulator-Acquiring Surface Proteins (BbCRASPs) are produced by B. burgdorferi, which are thought to assist spirochetes in host immune evasion. Recent studies established that BbCRASP-2 is preferentially expressed in mammals, and elicits robust antibody response in infected...

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Identifiers

PMID: 18714378
DOI: 10.1371/journal.pone.0003010
PMCID: PMC2526170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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