Article
Studying copy number variations using a nanofluidic platform.
Nucleic acids research - 1 Oct 2008
Qin Jian, Jones Robert C, Ramakrishnan Ramesh
Abstract excerpt
Copy number variations (CNVs) in the human genome are conventionally detected using high-throughput scanning technologies, such as comparative genomic hybridization and high-density single nucleotide polymorphism (SNP) microarrays, or relatively low-throughput techniques, such as quantitative polymerase chain reaction (PCR). All these approaches are limited in resolution and can at best distinguish a twofold (or...
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