Article
A genotypic assay for the amplification and sequencing of integrase from diverse HIV-1 group M subtypes.
Journal of virological methods - 1 Nov 2008
Van Laethem Kristel, Schrooten Yoeri, Covens Kris, Dekeersmaeker Nathalie, De Munter Paul, Van Wijngaerden Eric, Van Ranst Marc, Vandamme Anne-Mieke
Abstract excerpt
Recently, the Food and Drug Administration (FDA) of the USA approved the first integrase inhibitor for inclusion in treatment regimens of HIV-1 patients failing their current regimens with multi-drug resistant strains. However, treatment failure has been observed during integrase inhibitor-contai...
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