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Article

ICAM1 R241 is not associated with celiac disease in the Spanish population.

Human immunology - 1 Oct 2008

Dema Bárbara, Martínez Alfonso, Polanco Isabel, Maluenda Carlos, Fernández-Arquero Miguel, de la Concha Emilio G, Urcelay Elena, Núñez Concepción

Abstract excerpt

Celiac disease (CD) is a chronic intestinal inflammatory disease that develops in genetically susceptible individuals after gluten ingestion. The ICAM1 gene, located in the CD linkage region 19p13, encodes an intercellular adhesion molecule (ICAM-1) involved in inflammatory processes. Increased levels of ICAM-1 were observed in intestinal biopsies and in sera of CD patients. In addition, an association between...

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Source

Identifiers

PMID: 18703101
DOI: 10.1016/j.humimm.2008.07.009

Genes

ICAM1

Variants

rs5030400
rs5030400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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