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Article

Focal Gains of <i>VEGFA</i> and Molecular Classification of Hepatocellular Carcinoma

12 Aug 2008

Abstract excerpt

Hepatocellular carcinomas represent the third leading cause of cancer-related deaths worldwide. The vast majority of cases arise in the context of chronic liver injury due to hepatitis B virus or hepatitis C virus infection. To identify genetic mechanisms of hepatocarcinogenesis, we characterized copy number alterations and gene expression profiles from the same set of tumors associated with hepatitis C virus....

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PMID: 18701503
DOI: 10.1158/0008-5472.can-08-0742

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