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Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52

12 Aug 2008

Abstract excerpt

PURPOSE: Tumor protein D52 (TPD52 or D52) is frequently overexpressed in breast and other cancers and present at increased gene copy number. It is, however, unclear whether D52 amplification and overexpression target specific functional properties of the encoded protein. EXPERIMENTAL DESIGN: The expression of D52-like genes and MAL2 was compared in breast tissues using quantitative reverse transcription-PCR. The...

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PMID: 18698023
DOI: 10.1158/1078-0432.ccr-07-4994

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