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Increased Susceptibility to Mycobacterium avium in Hemochromatosis Protein HFE-Deficient Mice

11 Aug 2008

Abstract excerpt

Mycobacterium avium is an opportunistic infectious agent in immunocompromised patients, living inside macrophage phagosomes. As for other mycobacterial species, iron availability is a critical factor for M. avium survival and multiplication. Indeed, an association between host secondary iron overload and increased susceptibility to these mycobacteria is generally acknowledged. However, studies on the impact of...

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PMID: 18694968
DOI: 10.1128/iai.00612-08

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