Article
Mesenchymal stem cells effectively reduce surgically induced stenosis in rat carotids.
Journal of cellular physiology - 1 Dec 2008
Forte Amalia, Finicelli Mauro, Mattia Monica, Berrino Liberato, Rossi Francesco, De Feo Marisa, Cotrufo Maurizio, Cipollaro Marilena, Cascino Antonino, Galderisi Umberto
Abstract excerpt
Restenosis following vascular injury remains a pressing clinical problem. Mesenchymal stem cells (MSCs) promise as a main actor of cell-based therapeutic strategies. The possible therapeutic role of MSCs in vascular stenosis in vivo has been poorly investigated so far. We tested the effectiveness of allogenic bone marrow-derived MSCs in reduction of stenosis in a model of rat carotid arteriotomy. MSCs were...
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