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Analysis of genome-wide copy number variation in Irish and Dutch ALS populations.

Human molecular genetics - 1 Nov 2008

Cronin Simon, Blauw Hylke M, Veldink Jan H, van Es Michael A, Ophoff Roel A, Bradley Daniel G, van den Berg Leonard H, Hardiman Orla

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is an unrelenting neurodegenerative condition characterized by adult-onset loss of motor neurons. Genetic risk factors have been implicated in ALS susceptibility. Copy number variants (CNVs) account for more inter-individual genetic variation than SNPs and have...

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Identifiers

PMID: 18689356
DOI: 10.1093/hmg/ddn233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18689356-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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