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Article

A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer.

BMC cancer - 6 Aug 2008

Narita Naofumi, Yuasa Takeshi, Tsuchiya Norihiko, Kumazawa Teruaki, Narita Shintaro, Inoue Takamitsu, Ma Zhiyong, Saito Mitsuru, Horikawa Yohei, Satoh Shigeru, Ogawa Osamu, Habuchi Tomonori

Abstract excerpt

BACKGROUND: The purpose of this study was to evaluate the role of osteoprotegerin gene (OPG) polymorphisms as genetic modifiers in the etiology of prostate cancer (PCa) and disease progression. METHODS: Three hundred and sixty one patients with PCa and 195 normal controls were enrolled in the study, and two genetic polymorphisms, 149 T/C and 950 T/C in the putative promoter region of OPG, were genotyped. RESULTS:...

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Identifiers

PMID: 18684318
DOI: 10.1186/1471-2407-8-224
PMCID: PMC2527333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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