Article
Despite the lack of association between different genotypes and the presence of prostate cancer, endothelial nitric oxide synthase a/b (eNOS4a/b) polymorphism may be associated with advanced clinical stage and bone metastasis.
Urologic oncology - 1 Jan 2000
Sanli Oner, Kucukgergin Canan, Gokpinar Murat, Tefik Tzevat, Nane Ismet, Seckin Sule
Abstract excerpt
OBJECTIVES: To investigate the relationship between the distribution of endothelial NO synthase (eNOS4a/b) gene polymorphism and clinical features of prostate cancer (PCa). METHODS AND MATERIALS: One hundred thirty-two patients with PCa (mean age 64.10 ± 7.23 years) and 158 healthy controls (mean age 62.50 ± 7.53 years) with normal serum total prostate specific antigen (PSA) levels (<4 ng/ml) and digital rectal...
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