Article
Patterns of cytomegalovirus reactivation are associated with distinct evolutive profiles of immune reconstitution after allogeneic hematopoietic stem cell transplantation.
The Journal of infectious diseases - 15 Sept 2008
Moins-Teisserenc Hélène, Busson Marc, Scieux Catherine, Bajzik Véronique, Cayuela Jean-Michel, Clave Emmanuel, de Latour Régis Peffault, Agbalika Félix, Ribaud Patricia, Robin Marie, Rocha Vanderson, Gluckman Eliane, Charron Dominique, Socié Gérard, Toubert Antoine
Abstract excerpt
T cell-mediated immunity is essential for the control of cytomegalovirus (CMV) infections in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Our aims were to identify patterns of CMV-specific immune responses associated with multiple or prolonged reactivations. We analyzed findings in 116 recipients during the course of infection or reactivation and latency. CD8(+) T cell...
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