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Article

Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity.

Hepatology (Baltimore, Md.) - 1 Aug 2008

Lee Sang Seop, Cha Eun-Young, Jung Hyun-Ju, Shon Ji-Hong, Kim Eun-Young, Yeo Chang-Woo, Shin Jae-Gook

Abstract excerpt

UNLABELLED: Hepatocyte nuclear factor-4 alpha (HNF4A) is an essential transcriptional regulator for many genes that are expressed preferentially in the liver. Among the important functions of the liver is drug metabolism in response to xenobiotic exposure. Recent studies have suggested that HNF4A...

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PMID: 18666237
DOI: 10.1002/hep.22396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18666237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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