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Across array comparative genomic hybridization: A strategy to reduce reference channel hybridizations

28 Jul 2008

Abstract excerpt

Array comparative genomic hybridization (array CGH) is widely used for studying chromosomal copy number aberrations (CNAs) on a genome-wide and high-resolution scale in heritable disorders and cancers. The aim of this study was to test if the separate channels of dual channel arrays can be interchanged (across array) to either make array CGH more sensitive and cost effective and/or to generate profiles of CNAs...

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Share to Chromosomal and Genetic Variations
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PMID: 18663753
DOI: 10.1002/gcc.20605

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