Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel method for objective vision testing in canine models of inherited retinal disease.

Investigative ophthalmology & visual science - 1 Aug 2008

Gearhart Patricia M, Gearhart Chris C, Petersen-Jones Simon M

Abstract excerpt

PURPOSE: The use of canine models of retinal disease in the development of therapeutic strategies for inherited retinal disorders is a growing area of research. To evaluate accurately the success of potential vision-enhancing treatments, reliable methods for objectively assessing visual function in canine models is necessary. METHODS: A simple vision-testing device was constructed that consisted of a junction box...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choice Behavior
Share to Cyclic Nucleotide Phosphodiesterases, Type 6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Electroretinography

Share to False Positive Reactions

Share to Retina

Share to Retinal Degeneration

Share to Visual Acuity

Source

Identifiers

PMID: 18660425
DOI: 10.1167/iovs.07-0625

Genes

RPE65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel method for objective vision testing in canine models of inherited retinal disease.PMID 18660425Read ↗

The use of canine models of inherited retinal degeneration to test novel therapeutic approaches.Semantic proximity Read ↗

Evaluation of a behavioral method for objective vision testing and identification of achromatopsia in dogs.Semantic proximity Read ↗

Visualising treatment effects in low-vision settings: proven and potential endpoints for clinical trials of inherited retinal disease therapiesSemantic proximity Read ↗

A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs.Semantic proximity Read ↗

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epitheliumSemantic proximity Read ↗

Gene Therapy in a Large Animal Model of PDE6A-Retinitis PigmentosaSemantic proximity Read ↗

Cone-driven, geniculo-cortical responses in canine models of outer retinal diseaseSemantic proximity Read ↗

A novel form of progressive retinal atrophy in Swedish vallhund dogs.Semantic proximity Read ↗

Improvement of visual performance with intravitreal administration of 9-cis-retinal in Rpe65-mutant dogs.Semantic proximity Read ↗

Large Animal Models of Inherited Retinal Degenerations: A Review.Semantic proximity Read ↗

Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human PDE6A -Retinitis PigmentosaSemantic proximity Read ↗

Evaluation of the Toxicity and Efficacy of an Adeno-Associated Viral Vector Expressing BEST1 Delivered by Subretinal Injection in a Canine Model of Human Bestrophinopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.