Visualising treatment effects in low-vision settings: proven and potential endpoints for clinical trials of inherited retinal disease therapies

Abstract excerpt

Inherited retinal diseases are a devasting and incurable cause of blindness which frequently affect patients at a young age, and developing effective treatments has been an important research priority in recent decades. Treatments must be validated in randomised-control trials, which involve measuring benefit according to prospectively defined endpoints. A wide variety of conventional clinical endpoints and...

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