Article
A rare thalassemic syndrome caused by interaction of Hb Adana [alpha59(E8)Gly-->Asp] with an alpha+-thalassemia deletion: clinical aspects in two cases.
Hemoglobin - 1 Jan 2008
Douna Varvara, Papassotiriou Ioannis, Garoufi Anastasia, Georgouli Eleni, Ladis Vassilis, Stamoulakatou Alexandra, Metaxotou-Mavrommati Anna, Kanavakis Emmanuel, Traeger-Synodinos Joanne
Abstract excerpt
Hb Adana is a highly unstable and rare alpha-globin hemoglobin (Hb) variant, to date described in only three families, in interaction with other alpha-thalassemia (alpha-thal) deletions. We describe the clinical and hematological findings in two cases from independent families of Albanian origin, who have an interaction of the codon 59 (Gly-->Asp) alpha2-globin gene variant in trans to a 3.7 kb alpha(+)-thal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.